Eight fire engines and roughly 60 firefighters have been dispatched to a blaze on Rushey Green in Lewisham.
Crews are working to extinguish a fire at a three-storey nursery, where part of the roof is burning.
The Brigade's Control Office received the first of 17 emergency calls at 6:37pm and sent teams from Bromley, East Greenwich, Peckham and several nearby stations to the scene.
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